As someone who has had a brush with cancer myself, I know at first hand how invasive and unpleasant the current treatments are. That’s why the fireworks went off in my head when I read about the ‘Drug factory” beads implanted in mice’ that eliminated tumours within a week. And without causing damage to the surrounding healthy tissues!
Interleukin-2, a drug already approved by the FDA in the US, is made on-site by the drug factories [beads]. And the results were nothing short of miraculous:
“Once we determined the correct dose – how many factories we needed – we were able to eradicate tumors in 100 percent of animals with ovarian cancer and in seven of eight animals with colorectal cancer.”
Mice are not the same as humans so clinical trials will need to be carried out to see if this novel delivery system works as well in us as it does in lab animals, but we could be looking at a major revolution in the treatment of at least some cancers.
I’ve just completed a 5-page, 1700 word document that I can’t add to my nano wordcount. But guess what? I’m almost popping with joy. 🙂
The 5-page document is full of URLs and direct quotes copied during my research today. As I didn’t actually write any of it, I can’t claim it for nano, but the information I’ve found has finally answered the monster question that’s been plaguing me since November 1 – how did Bountiful go so very wrong?
For those who’ve never heard of Bountiful, it’s the name I gave to a synthetic food base fed to Refugees in the Innerscape trilogy. It caused terrible cancers and ultimately death before the cause was finally found. It’s also the reason Miira is in Innerscape, and the reason the assassin wants to kill Alex Tang.
I skirted the edges of Bountiful without going into a huge amount of detail about how it did what it did. I figured that information should come out in P7698. Unfortunately, I didn’t really have all those pesky details figured out when I started P7698 for nano. -sigh- Sometimes you really do have to jump in and hope for the best.
Unraveling Bountiful turned out to be a lot harder than expected because I am not a geneticist, not even a teeny bit close. Despite my extreme amateur status, however, I think I’ve finally got it, a possible explanation for why Bountiful was so deadly. It involves a gene called PTEN-L, genetic engineering and lateral gene transfer. And it’s awesome!
I have no idea how much of my research will actually end up in the book, probably very little, but at least what does go in will be possible, even if it’s not likely.